Search Limits	Search Field	Search Parameters
	spr name:	(e.g. spr0001)
	Gene name:	(e.g. dnaA)
	Molecule:	Protein  Nucleic Acid  Repeat unit
	Genome position:	Start:	End:
	Description:
	Notes:
	Molecular Weight:	Greater Than or Equal To:	Less Than or Equal To:
	pI:	Greater Than or Equal To:	Less Than or Equal To:
	Prosite motif:	2-oxo acid dehydrogenases acyltransferase component lipoyl binding site6-phosphogluconate dehydrogenase signature7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signatureAAA-protein family signatureABC transporters family signatureAcetate and butyrate kinases family signaturesAdenylate kinase signatureAdenylosuccinate synthetase signaturesAdipokinetic hormone family signatureADP-glucose pyrophosphorylase signaturesAlanine racemase pyridoxal-phosphate attachment siteAldehyde dehydrogenases active sitesAldo/keto reductase family signaturesAldose 1-epimerase putative active siteAlpha-galactosidase signatureAmidases signatureAminoacyl-transfer RNA synthetases class-I signatureAminoacyl-transfer RNA synthetases class-II signaturesAminopeptidase P and proline dipeptidase signatureAminotransferases class-I pyridoxal-phosphate attachment siteAminotransferases class-IV signatureAminotransferases class-V pyridoxal-phosphate attachment siteAP endonucleases family 1 signaturesArgE / dapE / ACY1 / CPG2 / yscS family signaturesArgininosuccinate synthase signaturesAsparaginase / glutaminase active sites signaturesAspartate and glutamate racemases signaturesAspartate and ornithine carbamoyltransferases signatureAspartokinase signatureATP synthase a subunit signatureATP synthase alpha and beta subunits signatureATP synthase c subunit signatureATP synthase gamma subunit signatureATP-dependent DNA ligase signaturesATP/GTP-binding site motif A (P-loop)Bacterial extracellular solute-binding proteins, family 1 signatureBacterial extracellular solute-binding proteins, family 3 signatureBacterial extracellular solute-binding proteins, family 5 signatureBacterial histone-like DNA-binding proteins signatureBacterial regulatory proteins, araC family signature and profileBacterial regulatory proteins, deoR family signatureBacterial regulatory proteins, gntR family signatureBacterial regulatory proteins, lacI family signatureBacterial regulatory proteins, luxR family signatureBacterial regulatory proteins, lysR family signatureBacterial ribonuclease P protein component signatureBacterial type II secretion system protein E signatureBeta-ketoacyl synthases active siteBeta-lactamases classes -A, -C, and -D active siteBinding-protein-dependent transport systems inner membrane componentC-5 cytosine-specific DNA methylases signaturesCarbamoyl-phosphate synthase subdomain signaturesCDP-alcohol phosphatidyltransferases signatureCecropin family signatureChaperonins clpA/B signaturesChaperonins cpn10 signatureChaperonins cpn60 signatureChorismate synthase signaturesCrystallins beta and gamma 'Greek key' motif signatureCyclophilin-type peptidyl-prolyl cis-trans isomerase signature & profileCys/Met metabolism enzymes pyridoxal-phosphate attachment siteCysteine proteases inhibitors signatureCysteine synthase/cystathionine beta-synthase P-phosphate attachment siteCytidine and deoxycytidylate deaminases zinc-binding region signatureCytochrome b/b6 signaturesCytochrome c family heme-binding site signatureCytochrome P450 cysteine heme-iron ligand signatureD-alanine--D-alanine ligase signaturesDEAD and DEAH box families ATP-dependent helicases signaturesDelta 1-pyrroline-5-carboxylate reductase signatureDihydrodipicolinate reductase signatureDihydrofolate reductase signatureDihydroorotase signaturesDihydroorotate dehydrogenase signaturesDihydropteroate synthase signaturesDihydroxy-acid and 6-phosphogluconate dehydratases signaturesDNA mismatch repair proteins mutL / hexB / PMS1 signatureDNA mismatch repair proteins mutS family signatureDNA polymerase family A signatureDNA repair protein radC family signatureDNA topoisomerase II signatureDNA/RNA non-specific endonucleases active siteDnaA protein signaturednaJ domains signatures and profileE1-E2 ATPases phosphorylation siteEF-hand calcium-binding domainElongation factor P signatureEndopeptidase Clp active sitesEndoplasmic reticulum targeting sequenceEnolase signatureEPSP synthase signaturesEukaryotic thiol (cysteine) proteases active sitesFerrochelatase signatureFGGY family of carbohydrate kinases signaturesFlavodoxin signatureFolylpolyglutamate synthase signaturesFormamidopyrimidine-DNA glycosylase signatureFormate--tetrahydrofolate ligase signaturesFructose-bisphosphate aldolase class-II signaturesFtsZ protein signaturesFumarate lyases signatureGalactokinase signatureGamma-glutamyl phosphate reductase signatureGHMP kinases putative ATP-binding domainGlu / Leu / Phe / Val dehydrogenases active siteGlucagon / GIP / secretin / VIP family signatureGlucose inhibited division protein A family signaturesGlucose-6-phosphate dehydrogenase active siteGlutamate 5-kinase signatureGlutamine amidotransferases class-I active siteGlutamine amidotransferases class-II active siteGlutamine synthetase signaturesGlutathione peroxidases signaturesGlyceraldehyde 3-phosphate dehydrogenase active siteGlycine radical signatureGlycoprotease family signatureGlycosyl hydrolases family 1 signaturesGlycosyl hydrolases family 32 active siteGlyoxalase I signaturesGonadotropin-releasing hormones signatureGram-positive cocci surface proteins 'anchoring' hexapeptidegrpE protein signatureGTP cyclohydrolase I signaturesGTP-binding elongation factors signatureGTP1/OBG family signatureHeat shock hsp70 proteins family signaturesHexapeptide-repeat containing-transferases signatureHIT family signatureHomoserine dehydrogenase signatureHydroxymethylglutaryl-coenzyme A reductase signatures and profileHypothetical cof family signaturesIMP dehydrogenase / GMP reductase signatureIndole-3-glycerol phosphate synthase signatureInitiation factor 3 signatureIron-containing alcohol dehydrogenases signaturesIsocitrate and isopropylmalate dehydrogenases signatureL-lactate dehydrogenase active siteLipases, serine active siteLipocalin signatureManganese and iron superoxide dismutases signatureMannitol dehydrogenases signatureMethylated-DNA--protein-cysteine methyltransferase active siteMIP family signatureMitochondrial energy transfer proteins signatureMulticopper oxidases signaturesmutT domain signatureMyb DNA-binding domain repeat signaturesMyc-type, 'helix-loop-helix' dimerization domain signatureN-6 Adenine-specific DNA methylases signatureNAD-dependent DNA ligase signaturesNeuraxin and MAP1B proteins repeated region signatureNeutral zinc metallopeptidases, zinc-binding region signatureNitrilases / cyanide hydratase signaturesNOL1/NOP2/sun family signatureNucleoside diphosphate kinases active siteOrn/DAP/Arg decarboxylases family 2 signaturesOrn/Lys/Arg decarboxylases family 1 pyridoxal-phosphate attachment siteOrotidine 5'-phosphate decarboxylase active sitePancreatic trypsin inhibitor (Kunitz) family signaturePEP-utilizing enzymes signaturesPeptidase family U32 signaturePeptidyl-tRNA hydrolase signaturesPeroxidases signaturespfkB family of carbohydrate kinases signaturesPhosphatidate cytidylyltransferase signaturePhosphoenolpyruvate carboxylase active sitesPhosphofructokinase signaturePhosphoglucomutase and phosphomannomutase phosphoserine signaturePhosphoglucose isomerase signaturesPhosphoglycerate kinase signaturePhosphopantetheine attachment sitePhosphoribosyl pyrophosphate synthetase signaturePhosphoribosylglycinamide synthetase signaturePhosphorylase pyridoxal-phosphate attachment sitePolyprenyl synthetases signaturesPrenyl group binding site (CAAX box)Prephenate dehydratase signaturesProkaryotic diacylglycerol kinase signatureProkaryotic DNA topoisomerase I active siteProkaryotic membrane lipoprotein lipid attachment siteProkaryotic transcription elongation factors signaturesProlipoprotein diacylglyceryl transferase signatureProtein kinases signatures and profileProtein secA signaturesProtein secY signaturesProtein smpB signaturePTS EIIA domains phosphorylation sites signaturesPTS EIIB domains cysteine phosphorylation site signaturePTS HPr component phosphorylation sites signaturesPurine and other phosphorylases family 1 signaturePurine and other phosphorylases family 2 signaturePurine/pyrimidine phosphoribosyl transferases signaturePutative AMP-binding domain signaturePyridine nucleotide-disulphide oxidoreductases class-I active sitePyridine nucleotide-disulphide oxidoreductases class-II active sitePyrrolidone-carboxylate peptidase active sitesRadical activating enzymes signaturerecA signaturerecF protein signaturesrecR protein signatureRegulator of chromosome condensation (RCC1) signaturesRiboflavin synthase alpha chain family Lum-binding site signatureRibonuclease II family signatureRibonuclease III family signatureRibonucleotide reductase large subunit signatureRibosomal protein L11 signatureRibosomal protein L13 signatureRibosomal protein L14 signatureRibosomal protein L15 signatureRibosomal protein L16 signaturesRibosomal protein L17 signatureRibosomal protein L19 signatureRibosomal protein L2 signatureRibosomal protein L20 signatureRibosomal protein L21 signatureRibosomal protein L22 signatureRibosomal protein L23 signatureRibosomal protein L24 signatureRibosomal protein L27 signatureRibosomal protein L3 signatureRibosomal protein L30 signatureRibosomal protein L31 signatureRibosomal protein L33 signatureRibosomal protein L34 signatureRibosomal protein L36 signatureRibosomal protein L5 signatureRibosomal protein L6 signaturesRibosomal protein L9 signatureRibosomal protein S10 signatureRibosomal protein S11 signatureRibosomal protein S12 signatureRibosomal protein S13 signatureRibosomal protein S14 signatureRibosomal protein S17 signatureRibosomal protein S18 signatureRibosomal protein S19 signatureRibosomal protein S2 signaturesRibosomal protein S21 signatureRibosomal protein S3 signatureRibosomal protein S4 signatureRibosomal protein S5 signatureRibosomal protein S7 signatureRibosomal protein S8 signatureRibosomal protein S9 signatureRibosomal RNA adenine dimethylases signatureRibulose-phosphate 3-epimerase family signaturesRlu family of pseudouridine synthase signatureRNA methyltransferase trmA family signaturesRNA polymerases beta chain signatureROK family signatureRsu family of pseudouridine synthase signatureS-100/ICaBP type calcium binding protein signatureS-adenosylmethionine synthetase signaturesSAICAR synthetase signaturesSerine carboxypeptidases, active sitesSerine hydroxymethyltransferase pyridoxal-phosphate attachment siteSerine proteases, subtilase family, active sitesSerine/threonine dehydratases pyridoxal-phosphate attachment siteSerpins signatureShikimate kinase signatureShort-chain dehydrogenases/reductases family signatureSigma-54 interaction domain signatures and profileSigma-70 factors family signaturesSignal peptidases I signaturesSodium:alanine symporter family signatureSoybean trypsin inhibitor (Kunitz) protease inhibitors family signatureSRP54-type proteins GTP-binding domain signatureSugar transport proteins signaturesTetrahydrofolate dehydrogenase/cyclohydrolase signaturesThiamine pyrophosphate enzymes signatureThiol-activated cytolysins signatureThiolases signaturesThioredoxin family active siteThymidine and pyrimidine-nucleoside phosphorylases signatureThymidine kinase cellular-type signatureThymidylate kinase signatureTonB-dependent receptor proteins signaturesTpx family signatureTransaldolase signaturesTransketolase signaturesTriosephosphate isomerase active siteTrp-Asp (WD-40) repeats signatureTryptophan synthase alpha chain signatureTryptophan synthase beta chain pyridoxal-phosphate attachment siteTubulin subunits alpha, beta, and gamma signatureTubulin-beta mRNA autoregulation signalUncharacterized protein family UPF0006 signaturesUncharacterized protein family UPF0011 signatureUncharacterized protein family UPF0019 signatureUncharacterized protein family UPF0029 signatureUncharacterized protein family UPF0030 signatureUncharacterized protein family UPF0031 signaturesUncharacterized protein family UPF0034 signatureUncharacterized protein family UPF0036 signatureUncharacterized protein family UPF0076 signatureUndecaprenyl pyrophosphate synthetase family signatureUracil-DNA glycosylase signatureWW/rsp5/WWP domain signature and profileXanthine/uracil permeases family signatureZinc-containing alcohol dehydrogenases signatures
	Role:	Amino acid BiosynthesisBiosynthesis of cofactors, prosthetic groups, and carriersBiosynthesis of polyaminesBiosynthesis of sugarsCell envelopeCellular processesCentral intermediary metabolismEnergy metabolismFatty acid and phospholipid metabolismHypotheticalOther categoriesPurines, pyrimidines, nucleosides, and nucleotidesRegulatory functionsRepeat unitReplicationRNATranscriptionTranslationTransport and binding proteinsUnassigned
	Subrole:	Amino acid Biosynthesis:Aromatic amino acidAmino acid Biosynthesis:Aspartate familyAmino acid Biosynthesis:Glutamate family/nitrogen assimilationAmino Acid Biosynthesis:Glycine-serine family/sulfur metabolismAmino acid Biosynthesis:Histidine familyAmino acid Biosynthesis:Pyruvate familyAmino acid Biosynthesis:Serine familyBiosynthesis of cofactors, prosthetic groups, and carriers:FAD biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers:Folic acidBiosynthesis of cofactors, prosthetic groups, and carriers:Heme and porphyrinBiosynthesis of cofactors, prosthetic groups, and carriers:LipoateBiosynthesis of cofactors, prosthetic groups, and carriers:Pyridine nucleotidesBiosynthesis of cofactors, prosthetic groups, and carriers:Pyridoxine biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers:RiboflavineBiosynthesis of cofactors, prosthetic groups, and carriers:thiaminBiosynthesis of cofactors, prosthetic groups, and carriers:ThiamineBiosynthesis of cofactors, prosthetic groups, and carriers:Thioredoxin, glutaredoxin, and glutathioneBiosynthesis of polyamines:Biosynthesis of polyaminesBiosynthesis of sugars:Biosynthesis of sugarsCell envelope:Membranes, lipoproteins, and porinsCell envelope:Murein sacculusCell envelope:Peptidoglycan biosynthesisCell envelope:Surface polysaccharides, lipopolysaccharides and antigensCell envelope:Surface structures and cytadherenceCellular processes:Cell divisionCellular processes:Cell killingCellular processes:ChaperonesCellular processes:Chemotaxis and mobilityCellular processes:CompetenceCellular processes:DetoxificationCellular processes:Osomotic adaptationCellular processes:Protein and peptide secretionCentral intermediary metabolism:Other metabolismCentral intermediary metabolism:Phosphorous compoundsEnergy metabolism:AerobicEnergy metabolism:Amino acids and aminesEnergy metabolism:AnaerobicEnergy metabolism:ATP-proton motive force interconversionEnergy metabolism:Broad regulatory functionsEnergy metabolism:FermentationEnergy metabolism:GlycolysisEnergy metabolism:OtherEnergy metabolism:Pentose Phosphate pathwayEnergy metabolism:Pyruvate dehydrogenaseEnergy metabolism:SugarsEnergy metabolism:TCAFatty acid and phospholipid metabolism:DegradationFatty acid and phospholipid metabolism:General fatty acidHypothetical:HypotheticalOther categories:Adaptations to atypical conditionsOther categories:Colicin-related functionsOther categories:Cryptic genesOther categories:Drug/analog sensitivityOther categories:OtherOther categories:Phage-related functions and prophagesOther categories:Plasmid related functionsOther categories:Pseudo geneOther categories:Radiation sensitivityOther categories:TransposaseOther categories:Virulence factorsPurines, pyrimidines, nucleosides, and nucleotides:2'-Deoyribonucleotide metabolismPurines, pyrimidines, nucleosides, and nucleotides:Nucleotide and nucleoside interconversionsPurines, pyrimidines, nucleosides, and nucleotides:Purine ribonucleotide biosynthesisPurines, pyrimidines, nucleosides, and nucleotides:Pyrimidine ribonucleotide biosynthesisPurines, pyrimidines, nucleosides, and nucleotides:Salvage of nucleosides and nucleotidesPurines, pyrimidines, nucleosides, and nucleotides:Sugar-nucleotide biosynthesis and conversionsRegulatory functions:General regulatoryRepeat unit:BOX repeat elementRepeat unit:RUP repeat elementReplication:DNA replicationReplication:RecombinationReplication:RepairReplication:Restriction, modificationRNA:ribosomal RNARNA:RNA degradationRNA:stable RNAsRNA:tRNATranscription:Degradation of RNATranscription:RNA synthesis, modification and DNA transcriptionTranscription:Transcription factorsTranslation:Amino acyl tRNA synthetases and tRNA modificationTranslation:Degradation of proteins, peptides, and glycopeptidesTranslation:General translationTranslation:Protein modificationTranslation:Protein modification and translation factorsTranslation:Ribosomal proteins: synthesis and modificationTranslation:translation; tRNA modificationTransport and binding proteins:ABC Superfamily: ATP-Binding ProteinTransport and binding proteins:ABC Superfamily: membrane spanning permeaseTransport and binding proteins:ABC Superfamily: substrate-binding proteinTransport and binding proteins:Amino acids, peptides and aminesTransport and binding proteins:AnionsTransport and binding proteins:Carbohydrates, organic alcohols, and acidsTransport and binding proteins:CationsTransport and binding proteins:F-type ATPaseTransport and binding proteins:General transportTransport and binding proteins:Ion channelsTransport and binding proteins:Other transportTransport and binding proteins:P-type ATPaseTransport and binding proteins:PTS transportTransport and binding proteins:Secondary transporter: Amino acid-polyamine-organocation (APC) superfamilyTransport and binding proteins:Secondary transporter: Glycoside-penotside-hexuronide (GPH):cation symport familyTransport and binding proteins:Secondary transporter: Major facilitator superfamilyTransport and binding proteins:Secondary transporter: Resistance-nodulation-cell devision (RND) superfamilyUnassigned:Unassigned